• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Watertight biopsy container, is a technical invention that refers to a watertight container that contains a solution of Formaldehyde and Formol in precise proportions for the collection of organic samples from patients. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2734413A1
    申请号:ES201800143
    申请日:2018-06-05
    公开日:2019-12-05
    发明作者:Parralo José Ramirez；Rodriguez José Antonio Gomez；Campos Juan José Moyano
    申请人:Instr Tecnica Analitica S L；
    IPC主号:
    专利说明:

    [0001]
    [0002] Waterproof container for biopsy.
    [0003]
    [0004] Technical sector
    [0005]
    [0006] Sanitary Technical Sector.
    [0007]
    [0008] Background of the invention
    [0009]
    [0010] From the research carried out through documents, bibliographies and patents that reflect the state of the art on the sealed biopsy container, some patents have been found, but analyzed each of them, not all the specifications that could be subject to have been found of protection and therefore differ from the proposed invention memory. Some of the most significant in the writing are enunciated.
    [0011]
    [0012] The present invention relates to a set of sealed container of plastic or other biopsy polyethylene formed by two hermetically sealed containers with a perfectly coupled lid, containing a liquid in solution of Formaldehyde and Formol in precise proportions for the collection of organic samples from patients. The invention has a manually operable device that allows to exchange the liquid in Formaldehyde and Formol solution from the upper container to the lower container, without opening it, to avoid gas emissions, nor the manipulation of said liquid. This means that there is no human or animal contact, nor possible inhalation of the liquid for health workers at the time of collecting the organic samples.
    [0013]
    [0014] Therefore, the invention of the sealed biopsy container is configured as a practical and useful solution to avoid inhaling, coming into contact or having exposures to formaldehyde. Royal Decree 665/2014 of the Commission modifies Regulation (C e ) 1272/2008 of the European Parliament or of the Council on classification and packaging of substances and mixtures. In it, it is established that formaldehyde is classified in category 1B as carcinogenic products. The International Agency for Research on Cancer (IARC) International Agency for Research on Cancer, published a monograph on formaldehyde in which it stated that there was sufficient evidence for humans, which produced cancer in the nasopharyngeal tract and leukemia.
    [0015]
    [0016] There are plastic packaging devices for autoclaving purposes such as the ES-2156896-T3 patent that describe a container concerned with the morphology of the plastic and its own composition. There are also others that are dedicated to manufacturing aseptic containers to house products, but none of them has a liquid-air exchanger device between biopsy containers, with guarantees of hermetic handling.
    [0017]
    [0018] Inventions are known that are intended for containers of liquid mixtures dedicated to cosmetics and perfumery such as patents ES-2213092-T3 and ES-2212231-T3 but they are patents that are not related to said invention. On the other hand we find a surgical biopsy device that is the ES-2292047-T3 patent intended for tissue sampling and, more particularly, for improved biopsy probes to obtain subcutaneous biopsies and to eliminate lesions, its approach is intended for taking of tissue samples inside the body, by aspiration, so it differs from the sample packaging that is formulated here.
    [0019] On the other hand, there are inventions related to the encapsulation of cultured tissues such as the ES-2231804-T3 patent but its purpose, form and arrangement are totally different from the patent of the sealed biopsy container.
    [0020]
    [0021] Mixers between products, whether liquid or powder, are known, such as document ES-2032670-T3, and those containers designed to minimize the risk of spills or accidental splashes when using highly hazardous products, a fact mentioned in the state of the art of patent ES-2097113 intended for packaging for toxic liquid products. Another adapter recently patented an adapter for the tight sealing of containers or containers with the international application WO 2017/203087 A1, this, is nothing more than a closing adapter for containers for biological or chemical products. Your device focuses on the seal to avoid dangerous contamination. It does not have any liquid exchanger nor is it intended for the transport and conservation of biopsy.
    [0022]
    [0023] The invention "Sealable vessel for containing and Processing analytical samples" EP 0609431 B1 of the state of California, describes an airtight container for storing an analytical sample for processing. The container includes a body, with a dispensing port and an insertion member slidably received in the body. The container is particularly adapted to contain the nucleic acid amplification processes and thus reduce the problems of cross contamination of the samples found in such processes. It differs from the invention that is requested in that the device is totally different, since it is not a tight container that ensures the liquid tightness and the discharge of the existing liquid that is drip.
    [0024]
    [0025] The proposed invention moves away from the objectives of the previous ones, with the main objective being to conserve in a superior container (8) the liquid in solution of Formaldehyde and Formol, which, as we have indicated in practical solution, must be avoided inhalation and contact the humans. For this, by means of a device and once the organic sample is taken and deposited in the lower container (11) by manual pressure of the connection (1), (3) and (6) that is plugging the upper liquid, it It will pass from the upper container (8) to the lower container (11) that has the organic sample deposited.
    [0026]
    [0027] Explanation of the invention.
    [0028]
    [0029] The assembly forms a sealed and airtight disposable plastic container with a disintegration valve from the biopsy sample, thus avoiding human contact with the liquid.
    [0030] To summarize the phases of the procedure that allows to develop the patent are listed in five.
    [0031]
    [0032] i. In a first phase the lower plastic container (11) is opened and the organic biopsy sample is deposited
    [0033]
    [0034] ii. In a second phase, once the lower plastic container is closed tightly and placing a plasticized seal identifying that there is a sample, the safe ring (12) will be removed from the manual actuation device that releases the liquid from the plastic container superior to the lower plastic container.
    [0035]
    [0036] iii. In a third phase, the plug (1) is operated manually and with downward pressure releasing the solution of Formaldehyde and Formol in precise proportions from the upper container to the lower container. From this moment the organic sample contains the solution and the airtight container can be transported With full guarantee. The tightness of the assembly means that it can be transported without problem. Even so, an adhesive tape will be placed to avoid external manipulation during transport.
    [0037]
    [0038] Once the information is collected, it is verified that there is no product similar to the invention presented and that it has such a specific objective as the plastic packaging set that allows to have a liquid in solution of Formaldehyde and Formol in precise proportions for the collection of organic samples of patients. The advantages of being two watertight containers arranged vertically one above the other, facilitate gravity transfer of the liquid.
    [0039]
    [0040] Brief description of the drawings
    [0041]
    [0042] An additional example of a container according to this invention is described below, with reference to the accompanying drawings, in which:
    [0043]
    [0044] Figure 1. It is an elevation view and a sectional view of the liquid exchanger device.
    [0045]
    [0046] Figure 2. It shows the section of the two watertight containers, the drive device through an exploded view of its elements that conform it along its axis.
    [0047] Figure 3. It shows the section of the two watertight containers and the actuator, perfectly hermetically anchored and all together.
    [0048]
    [0049] Figure 4. Shows half of a longitudinal radial section and half in linear projection of the entire package as a whole.
    [0050]
    [0051] Figure 5. The sealed biopsy container assembly appears in perspective.
    [0052]
    [0053] Preferred Embodiment of the Invention
    [0054]
    [0055] In view of these figures it can be seen that the biopsy sealed container is essentially constituted by two hermetic containers with their corresponding caps that fit perfectly, one on top of the other, to which a cylindrical rod is added that serves as a manual actuation device for exchange the cited liquid. The invention is based on this device that allows the Formaldehyde and Formo solution to pass through gravity in precise proportions for the collection of organic samples from patients without coming into liquid contact with the operator or sample manipulator. This is the key to the success of the invention. The design of the rod that has a plug threaded to be disassembled, allows a tight mechanism that prevents the drainage of liquid from one container to another.
    [0056]
    [0057] With reference to the details of the drawings showing the different figures, in which similar numbers indicate the same elements along the views, sections and perspectives, the present invention is illustrated which relates to a sealed container for biopsies.
    [0058]
    [0059] The set refers to two containers (8) and (11) with their respective hermetic caps (7) and (10).
    [0060] They form a cylindrical assembly that can be manufactured is different sizes that will depend on the dimensions of the biopsy sample. Both sealed containers can be made of any moldable polymer material, such as polyethylene, polypropylene, polyester or PET of a thickness of approximately 1.5 mm. The lid that closes the lower container (11) is attached to the upper container (8) by means of a specially designed ring (9) to serve as an adapter to the closure plug (5). The liquid exchange device with Formaldehyde and Formol solution in precise proportions, consists of three elements: Bottom Cap (5) that has a circular groove where a rubber O-ring or 0-Ring (6) is housed whose function is to ensure the tightness of the liquid or fluid. Said cap is attached to a circular rod (3) that is threaded at its end. The last element located at the top is a threaded plug (1) that drives the liquid evacuation and is connected to said cylindrical rod by means of a metric thread. Said plug has a circular groove where a rubber rubber or O-Ring gasket (2) is housed. The arrangement of the rod is perfectly anchored between the two containers, by means of the rings (4) and (9) that serve as an axis, once the pieces (5), (3) and (1) are completely screwed.
    [0061]
    [0062] It is not considered necessary to make this description more extensive since it is understood that any person skilled in the art will understand the scope of the invention and the advantages in the subject of sealed containers for biopsy and liquid exchanger between packages and the advantages of such Invention are derived.
    [0063]
    [0064] The materials, shape, size and arrangement of the elements will be susceptible to variation, without this implying an alteration to the essentiality of the invention.
    [0065]
    [0066] The assembly process of the present invention is carried out in the following order: first, the ring (4) is adhered to the top lid of the container (8) by elastic glue that fixes the moldable polymer. In the same way, the ring (9) is fixed to the top lid of the container (11) with the seat or ass of the container (8) constituting a joint piece as shown in figure 2. With the manufacture of the rod which constitutes the pieces (1), (3) (5) and (6) the manufacturing process of the sealed biopsy container is completed. The handling process for the discharge of cancerous liquids must be manipulated in their manufacture by a specialist and in accordance with the regulations in this regard. Once the invention of the watertight biopsy vessel is manufactured, and for the pouring of the liquid in solution of Formaldehyde and Formol in precise proportions, it must be ensured that the rod constituted by the pieces (1), (3) and (5), is located perfectly anchored in the ring (9) to avoid spilling said liquid (closing position). The process ends when the upper cover (7) is tightly placed and the cap (1) is threaded to the part (3) at its highest pressure. The final assembly phase ends by placing a safety ring (12), to prevent accidental operation of the liquid exchanger.
    [0067]
    [0068] To complete the descriptions that are being made and in order to help a better understanding of the characteristics of the invention, this descriptive report is attached, forming an integral part thereof, of two sheets of plans in which for illustrative purposes and non-limiting, the following has been represented:
    [0069]
    [0070] Figure 1.- Shows an elevation view and a sectional view of the rod that makes the liquid exchange device.
    [0071]
    [0072] Figure 2.- It shows the cross section of the two watertight containers, the drive device through an exploded view of its elements.
    [0073]
    [0074] Figure 3.- Shows the section of the two watertight containers and the actuator, perfectly hermetically anchored and all in its entirety.
    [0075]
    [0076] Figure 4.- Shows half of a longitudinal radial section and half in linear projection of the entire package as a whole.
    [0077]
    [0078] Figure 5 shows in perspective the assembly of the sealed biopsy container.
    权利要求:
    Claims (1)
    [1]
    1. Disposable sealed biopsy container that forms a set of two airtight containers (8) and (11) with their respective covers (7) and (10). They form a cylindrical assembly that can be manufactured is different sizes that will depend on the dimensions of the biopsy sample. Both sealed containers can be made of any moldable polymer material, such as polyethylene, polypropylene, polyester or PET of a thickness of approximately 1.5 mm. Characterized because by means of a device and once the organic sample is taken and deposited in the lower container (11) by manual pressure of the connect and the rod (1), (3) and (6) that is plugging the upper liquid , this will pass from the upper container (8) to the lower container (11) that has the organic sample deposited. There is an exchange of liquid from the upper to the lower container that has the organic sample without emanation of gases, or danger of handling. The proposed invention moves away from the objectives of the aforementioned inventions, with the main objective being to conserve in a superior container (8) the liquid in solution of Formaldehyde and Formol, which, as we have indicated in practical solution, should be avoided inhalation and contact with the humans.
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    同族专利:
    公开号 | 公开日
    ES2734413B2|2020-09-04|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US5460283A|1991-01-25|1995-10-24|Macartney; Charles T.|Sealing closure cap|
    WO2016131859A1|2015-02-20|2016-08-25|Ventana Medical Systems, Inc.|Assembly for storing and transporting tissue samples immersed in a fluid|
    KR20170003384U|2016-03-21|2017-09-29|패스텍|Removable biopsy container|
    KR101736745B1|2016-11-16|2017-05-29|김종민|Specimen container for preserving tissue|
    法律状态:
    2019-12-05| BA2A| Patent application published|Ref document number: 2734413 Country of ref document: ES Kind code of ref document: A1 Effective date: 20191205 |
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    优先权:
    申请号 | 申请日 | 专利标题
    ES201800143A|ES2734413B2|2018-06-05|2018-06-05|Watertight container for biopsy|ES201800143A| ES2734413B2|2018-06-05|2018-06-05|Watertight container for biopsy|
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